姓 名：叶晓东
出 生：1979年03月出生于江苏
地 址：安徽省合肥市金寨路96号中国科学技术大学化学物理系(230026)
电 话：86-551-63606742 (O)
邮 件：xdye@ustc.edu.cn
主 页 : http://staff.ustc.edu.cn/~xdye
教育和研究经历
2014.6-至今，中国科学技术大学，化学物理系，副教授
2008.6-2009.9，杜克大学，生物制药工程系，访问学者
2007.12-2014.6，中国科学技术大学，化学物理系，讲师
2006.9-2007.9，香港中文大学，化学系，博士后
2000-2006，中国科学技术大学，化学物理系，博士
1996-2000，中国科学技术大学，化学物理系，本科
研究兴趣
1.大分子折叠动力学
2.药物载体的设计与合成
3.DNA与离子, 有机小分子和蛋白质间相互作用
采用的研究方法包括:激光光散射(LLS), 分析型超速离心(AUC)和差示扫描量热法(DSC)等. 欢迎感兴趣的同学报考本实验室研究生，也欢迎各年级本科生到实验室学习或做毕业论文。
教学经历
物理化学(II)，2010-现在
分子间的相互作用力，2011-现在
应用物理化学(I)，2016-现在
在研项目
主持国家自然科学基金面上项目“分析型超速离心用于不同拓扑结构的聚合物的表征”2017-2020
代表论文
1. Ni, K.; Gao, Y.T.; Ye, X.D.* “Study on the Structure and Formation Mechanism of 15S Globulin of Soybeans”, Food Hydrocolloids Article Number 106461.
2. Zhang, M.; Hao, N.R.; Gao, Y.T.; Li, L.W.; Ye, X.D.* “Characterization of Mixed Solutions of Hyperbranched and Linear Polystyrenes by a Combination of Size-exclusion Chromatography and Analytical Ultracentrifugation”, Journal of Polymer Science 58, 756-765 (2020)
3. Si, J.H.*; Hao, N.R.; Zhang, M.; Cheng, S.Y.; Liu, A.H.; Li, L.W.* and Ye, X.D.* “Universal Synthetic Strategy for the Construction of Topological Polystyrenesulfonates: The Importance of Linkage Stability during Sulfonation”, ACS Macro Lett8, 730-736 (2019)
4. Yang, J.X.*; Li, Y.X.; Hao, N.R.; Umair, A.; Liu, A.H.; Li, L.W.* and Ye, X.D.* “Preparation and Controlled Degradation of Model Amphiphilic Long-Subchain Hyperbranched Coipolymers: Hyperblock versus Hypergraft”, Macromolecules52, 1173-1187 (2019)
5. Li, Y.X.; Si, J.H.; Fan, H.Y.; Ye, X.D.* “Effect of pH and Content of Reduction-Sensitive Copolymer on the Guest Exchange Kinetics of Micelles”, Journal of Polymer Science Part B: Polymer Physics. 56, 1636-1644 (2018)
6. Gao, Y.T.; Guang, T.L.; Ye, X.D.* “Sedimentation Velocity Analysis of TMPyP4-induced Dimer Formation of Human Telomeric G-quadruplex”, RSC Advances7, 55098-55105 (2017)
7. Fan, H.Y.; Li, Y.X.; Yang, J.X.; Ye, X.D.* “Effect of Hydrophobic Chain Length on the Stability and Guest Exchange Behavior of Shell-Sheddable Micelles Formed by Disuflide-Linked Diblock Copolymers”, TheJournal of Physical Chemistry B121, 9708-9717 (2017)
8. Yang, J.X.; Li, L.W.; Ma, C.F.; Ye, X.D.* “Degradable polyurethane with poly(2-ethyl-2-oxazoline) brushes for protein resistance”, RSC Advances6, 69930-69938 (2016)
9. Gao, Y.T.; Wu, S.; Ye, X.D.* “The effects of monovalent metal ions on the conformation of human telomere DNA using analytical ultracentrifugation, Soft Matter12, 5959-5967 (2016)
10. Gao, Y.T.; Yang, J.X.; Fan, H.Y.; Ding, Y.W.; Ye, X.D.* “Insight into the effect of methylated urea on the phase transition of aqueous solutions of poly(N-isopropylacrylamide) by microcalorimetry: hydrogen bonding and van der Waals interactions, Journal of Polymer Science Part B: Polymer Physics. 54, 1145 (2016)
11. Du, X.J.; Wang, J.L.; Liu, W.W.; Yang, J.X.; Sun, C.Y.; Sun, R.; Li, H.J.; Shen, S.; Luo, Y.L.; Ye, X.D.*; Zhu, Y.H.; Yang, X.Z.; Wang, J.* “Regulating the surface poly(ethylene glycol) density of polymeric nanoparticles and evaluating its role in drug delivery in vivo, Biomaterials69, 1-11 (2015)
12. Wang, X.Y.; Ye, X.D.*; Zhang, G.Z. “Investigation of pH-induced Conformational Change and Hydration of Poly(methacrylic acid) by Analytical Ultracentrifugation, Soft Matter11, 5381-5388 (2015)
13. Yang, J.X.; Li, L.W.*; Jing, Z.Y.; Ye, X.D.*; Wu, C. “Construction and Properties of Hyperbranched Block Copolymer with Independently Adjustable Heterosubchains, Macromolecules47, 8437-8445 (2014)
14. Wang, X.; Li, L.W.*; Ye, X.D.*; Wu, C. “Comparative Study of Solution Properties of Amphiphilic 8-shaped Cyclic-(Polystyrene-b-Poly(acrylic acid))2 and Its Linear Precursor”, Macromolecules47, 2487-2495 (2014)
15. Li, L.W.*; Wang, X.; Yang, J.X.; Ye, X.D.*; Wu, C. “Degradation Kinetics of Model Hyperbranched Chains with Uniform Subchains and Controlled Locations of Cleavable Disulfide Linkages”, Macromolecules47, 650-658 (2014)
16. Gao, Y.T.; Yang, J.X.; Ding, Y.W.; Ye, X.D.* “Effect of Urea on Phase Transition of Poly(N-isopropylacrylamide) Investigated by Differential Scanning Calorimetry”, TheJournal of Physical Chemistry B 118, 9460-9466 (2014)
17. Wu, S.; Wang, X.Y.; Ye, X.D.*; Zhang, G.Z.* “pH-induced Conformational Change and Dimerization of DNA Chains Investigated by Analytical Ultracentrifugation”, TheJournal of Physical Chemistry B 117, 11541-11547 (2013)
18. Ye, X.D.*; Yang, J.X.; Ambreen, J. “Scaling Laws between the hydrodynamic parameters and molecular weight of linear poly(2-ethyl-2-oxazoline)”, RSC Advances3, 15108-15113 (2013)
19. Lu, Y.J.; Ye, X.D.*; Zhou, K.J.; Shi, W.J. “A Comparative Study of Urea-induced Aggregation of Collapsed Poly(N-isopropylacrylamide) and Poly(N,N-diethylacrylamide) Chains in Aqueous Solutions”, TheJournal of Physical Chemistry B 117, 7481-7488 (2013)
20. Wang, L.F.; Wang, L.L.; Ye, X.D.*; Li, W.W.; Ren, X.M.; Sheng, G.P.; Yu, H.Q.*; Wang, X.K. “Coagulation Kinetics of Humic Aggregates in Mono- and Di-valent Electrolyte Solutions”, Environmental Science and Technology47, 5042-5049 (2013)
21. Wang, L.L.; Wang, L.F.; Ren, X.M.; Ye, X.D.*; Li, W.W.; Yuan, S.J.; Sun, M.; Sheng, G.P.; Yu, H.Q.*; Wang, X.K., “pH Dependence of Structure and Surface Properties of Microbial EPS”, Environmental Science and Technology46, 737-744 (2012)
22. Lu, Y.J.; Ye, X.D.*; Li, J.F.; Li, C.L.; Liu, S.L. “Kinetics of Laser-Heating-Induced Phase Transition of Poly(N-isopropylacrylamide) Chains in Dilute and Semidilute Solutions”, The Journal of Physical Chemistry B.115, 12001-12006 (2011)
