姓名：张亮
联系电话：18779686695
地址：中国科学技术大学 化学物理系 合肥金寨路96号
电子邮箱：zhangliang2025@ustc.edu.cn
教育经历
2008.09 – 2012.07 井冈山大学 理学学士
2012.09 – 2015.03 同济大学 理学硕士
2015.09 – 2019.12 武汉大学 工学博士
工作经历
2019.10 – 2021.12 武汉大学 博士后 导师：孙志军、邓鹤翔教授
2021.12 – 2025.03 香港科技大学 博士后 导师：唐本忠院士
2025.03 – 至今 中国科学技术大学 特任研究员
主要研究兴趣
人工智能（AI）赋能光学功能晶态多孔材料（MOF、COF、HOF等）的精准智能创制，并探索它们在生命健康、能源转换等领域的应用。
主要研究方向
1.精准化、智能化双驱动的AIE COF材料的精准智能创制及机制研究。
2. AI助力优异光物理性质（如光致、电致、压致、力致发光、室温磷光及多光子荧光等）晶态多孔材料精准智能合成。
3. AI助力功能和应用导向的MOF、COF、HOF等材料的个性化定制、规模化、标准化、大批量制备及其在生命健康、能源转换等领域的应用
代表论文
1. Liang Zhang†, Shuo Wang†, Qi-Chao Yang†, An Song, Yuan-Yuan Wang, Wen-Da Wang, Meng-Jie Zhang, Hao Li, Zhi-Jun Sun*, Hexiang Deng*, “Bimetallic Covalent Organic Framework Trigger PANoptosis for Efficient Radiotherapy” Adv. Mater.2025, 37, 2413002.
2. Liang Zhang†, Boxin Zhang†, Meng-Jie Zhang†, Wenlang Li, Hao Li, Yantian Jiao, Qi-Chao Yang, Shuo Wang, Yuan-Tong Liu, An Song, Hai-Tao Feng, Jianwei Sun, Ryan T. K. Kwok, Jacky W. Y. Lam*, Ben Zhong Tang*, Zhi-Jun Sun*, “Trigger Inducible Tertiary Lymphoid Structure Formation using Covalent Organic Frameworks for Cancer Immunotherapy” Nat. Commun.2025, 16, 1-14.
3. Qi-Chao Yang, Yuan-Yuan Wang, Shuo Wang, An Song, Wen-Da Wang, Liang Zhang*, Zhi-Jun Sun*, “Fusobacterium nucleatum membrane-camouflaged covalent organic frameworks as nanoimmuno-potentiator for cancer immunotherapy” Bioact. Mater.2025, 47, 283-294.
4. Liang Zhang†, An Song†, Qi-Chao Yang, Shu-Jin Li, Shuo Wang, Shu-Cheng Wan, Jianwei Sun, Ryan T. K. Kwok, Jacky W. Y. Lam*, Hexiang Deng*, Ben Zhong Tang*, Zhi-Jun Sun*, “Integration of AIEgens into Covalent Organic Frameworks for Pyroptosis and Ferroptosis Primed Cancer Immunotherapy” Nat. Commun.2023, 14, 5355.
5. Liang Zhang†, Fuding Guo†, Saiting Xu, Qiang Deng, Mengjie Xie, Jianwei Sun, Ryan T. K. Kwok, Jacky W. Y. Lam, Hexiang Deng*, Hong Jiang*, Lilei Yu* Ben Zhong Tang*, “AIEgen-based Covalent Organic Frameworks for Preventing Malignant Ventricular Arrhythmias Via Local Hyperthermia Therapy” Adv. Mater.2023, 35, 2304620.
6. Liang Zhang†, Shu-Cheng Wan†, Jianyu Zhang†, Meng-Jie Zhang, Qi-Chao Yang, Boxin Zhang, Wu-Yin Wang, Jianwei Sun, Ryan T. K. Kwok, Jacky W. Y. Lam*, Hexiang Deng*, Zhi-Jun Sun*, Ben Zhong Tang*, “Activation of Pyroptosis Using AIEgen-Based sp2 Carbon-Linked Covalent Organic Frameworks” J. Am. Chem. Soc.2023, 145, 17689-17699.
7. Liang Zhang†, Qi-Chao Yang†, Shuo Wang, Yao Xiao, Shu-Cheng Wan, Hexiang Deng*, Zhi-Jun Sun*, “Engineering Multienzyme-Mimicking Covalent Organic Frameworks as Pyroptosis Inducers for Boosting Antitumor Immunity” Adv. Mater.2022, 34, 2108174.
8. Liang Zhang†, Yi Zhou†, Mei Jia†, Yiwen He, Wei Hu, Qi Liu, Jing Li, Xiaohui Xu, Chao Wang, Anna Carlsson, Sorin Lazar, Arno Meingast, Yanhang Ma, Jun Xu, Wen Wen, Zhihong Liu, Jun Cheng, Hexiang Deng*, “Covalent Organic Framework for Efficient Two-Photon Absorption” Matter2020, 2, 1049-1063.
9. Liang Zhang†, Shibo Wang†, Yi Zhou, Chao Wang, Xian-Zheng Zhang, Hexiang Deng*, “Covalent Organic Frameworks as Favorable Constructs for Photodynamic Therapy” Angew. Chem. Int. Ed.2019, 58, 14213-14218.
10. Yanqiu Duan†, Yang Yu†, Peilai Liu†, Yao Gao, Xinyue Dai, Liang Zhang*, Liang Chen*, Yu Chen*, “Reticular Chemistry-Enabled Sonodynamic Activity of Covalent Organic Frameworks for Nanodynamic Cancer Therapy” Angew. Chem. Int. Ed.2023, 62, e202302146.
11. Liang Zhang†, Yao Xiao†, Qi-Chao Yang, Lei-Lei Yang, Shu-Cheng Wan, Shuo Wang, Lu Zhang,* Hexiang Deng, Zhi-Jun Sun* “Staggered Stacking Covalent Organic Frameworks for Boosting Cancer Immunotherapy” Adv. Funct. Mater.2022, 32, 2201542.
12. Liang Zhang†, Lei-Lei Yang†, Qi-Chao Yang, Shu-Cheng Wan, Yao Xiao, Hexiang Deng*, Zhi-Jun Sun*, “3D Covalent Organic Frameworks with Cross-linked Pores for Efficient Cancer Immunotherapy” Nano. Lett.2021, 21, 7979-7988.
13. Boxin Zhang†, Liang Zhang†, Wuyin Wang, Enli Yang, An Song, Dian Xiong, Qi-chao Yang, Hexiang Deng*, Zhi-Jun Sun* “Single-Cell RNA-Sequencing-Aided Covalent Organic Frameworks-Based Microneedle Design Targeting Phototherapy Resistant Tumor Cell” Adv. Funct. Mater.2024, 34, 2313890.
14. Liang Zhang†, Lezhi Yi†, Zhi-Jun Sun, Hexiang Deng*, “Covalent organic frameworks for optical applications” Aggregate.2021, 2, e24.
15. Lei-Lei Yang†, Liang Zhang†, Shu-Cheng Wan, Shuo Wang, Zhi-Zhong Wu, Qi-Chao Yang, Yao Xiao, Hexiang Deng*, Zhi-Jun Sun*, “Two-Photon Absorption Induced Cancer Immunotherapy Using Covalent Organic Frameworks” Adv. Funct. Mater.2021, 31, 2103056.
16. Kai Feng†, Liang Zhang†, Jiang Gong*, Jinping Qu, Ran Niu*, “Visible light triggered exfoliation of COF micro/nanomotors for efficient photocatalysis” Green Energy & Environment2023, 8, 567-578.